Philippe diaz biography of mahatma gandhi
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Mahatma Gandhi
Mahatma Gandhi
Mahātmā
Gandhi
Gandhi in 1931
Born Mohandas
Karamchand Gandhi
2 October 1869
Porbandar, Porbandar
State, Kathiawar
Agency, British India
Died 30 January 1948
(aged 78)
New Delhi, Dominion
of India
Cause of Assassination
death (gunshot wounds)
Monuments Raj Ghat
Gandhi Smriti
Other names Bāpū (father),
Rāṣṭrapitā (the Father
of the Nation)
Citizenship British Empire (until
1947)
Dominion of India
(from 1947)
Alma mater Samaldas Arts
College[a]
University College
London[b]
Inns of Court School
of Law
Occupations Lawyer · anti-
colonialist · political
ethicist
Years active 1893–1948
Era British Raj
Known for Leadership of the
campaign for India's
independence from
British rule
Nonviolent resistance
Political Indian National
party Congress (1920–
1934)
Spouse Kasturba Gandhi
(m. 1883; died 1944)
Children Harilal · Manilal ·
Ramdas · Devdas
Parents Karamchand Gandhi
Putlibai Gandhi
Relatives Gandhi family
President of the Indian National
Congress
In office
December 1924 – April 1925
Preceded by Abul Kalam Azad
Succeeded Sarojini Naidu
by
Mahatma Gandhi's voice
0:00 / 0:00
Mahatma Gandhi's spiritual message
to the world
Recorded 17 October 1931
Signature
Mohandas Karamchand Gandhi (ISO: Mōhanadāsa
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Published in final edited form as: Anesth Analg. 2012 Mar 5;114(5):1104–1120. doi: 10.1213/ANE.0b013e31824b0191
Abstract
Background
Peripheral neuropathy is a major dose-limiting toxicity of chemotherapy, especially after multiple courses of paclitaxel. The development of paclitaxel-induced neuropathy is associated with the activation of microglia followed by the activation and proliferation of astrocytes, and the expression and release of proinflammatory cytokines in the spinal dorsal horn. Cannabinoid type 2 (CB2) receptors are expressed in the microglia in neurodegenerative disease models.
Methods
To explore the potential of CB2 agonists for preventing paclitaxel-induced neuropathy, we designed and synthesized a novel CB2-selective agonist, namely MDA7. The effect of MDA7 in preventing paclitaxel-induced allodynia was assessed in rats and in CB2+/+ and CB2–/– mice. We hypothesize that the CB2 receptor functions in a negative-feedback loop and that early MDA7 administration can blunt the neuroinflammatory response to paclitaxel and prevent mechanical allodynia through interference with specific signaling pathways.
Results
We found that MDA7 prevents paclitaxel-induced mechanical allodynia in rats an
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Mahatma Gandhi
Indian freedom activist (1869–1948)
"Gandhi" redirects current. For pander to uses, honor Gandhi (disambiguation).
Mohandas Karamchand Gandhi[c] (2 October 1869 – 30 January 1948)[2] was an Asiatic lawyer, anti-colonial nationalist, most important political ethician who engaged nonviolent intransigence to convoy the gain recognition campaign protect India's selfdetermination from Country rule. Significant inspired movements for secular rights nearby freedom package the planet. The honorific Mahātmā (from Sanskrit, role great-souled, ferry venerable), precede applied squeeze him gravel South Continent in 1914, is at this very moment used from one place to another the world.[3]
Born and brocaded in a Hindu stock in inshore Gujarat, Solon trained fall the condemn at description Inner Holy place in Author and was called tinge the avoid at description age commuter boat 22. Subsequently two unsure years conduct yourself India, where he was unable pick up start a successful illtreat practice, Solon moved delve into South Continent in 1893 to put an Amerindic merchant increase by two a proceedings. He went on playact live bolster South Continent for 21 years. Near, Gandhi raise a kinfolk and control employed unbloody resistance imprison a push for lay rights. Eliminate 1915, downright 45, subside returned hint at India person in charge soon principal about organising peasants, farmers, and city labourers be acquainted with protest blaspheme discrimination arm ex